Ultimate Spider-Man, Vol. 1

Peter is freaked out over the Scorpion's face, so he does the only thing he can think of: he brings it to the Fantastic Four. They examine it, and find it a 94.2% DNA match to Peter Parker. He has to leave to see Aunt May before they can investigate much further. He plans to get back ASAP, but gets sidetracked when he learns Mary Jane is missing. His search for her finds something completely different, in the form of a woman with spider powers. That can't even begin to prepare him for what he finds in his old house, though.