Paracelsus turns the warehouse into a house of horrors. Can the team stop him in time?

Pete and Myka return to Washington DC, to investigate a series of victims drowning on dry land where they run into a pair of fellow Secret Service agents with a surprising secret - a secret which forces Myka and Pete to evaluate where their own relationship has taken them. Meanwhile, Artie uses an artifact to take Claudia back into his memories of an old case, to show her the truth about her sister.

Pete and Steve immerse themselves in a Renaissance Faire as they search for a dangerous artifact which animated both a horseless chariot and a life-size chess piece and set them against the faire patrons. Meanwhile, Claudia risks combining artifacts in a desperate attempt to revive her sister Claire from her artifact-induced coma; Myka struggle to prevent Artie from finding out and stopping her.

Pete, Myka, and Artie help Kelly Hernandez (Pete's ex-girlfriend) save her grandmother who is trapped inside a Telenovela, and in the process "fall in" and become characters of this Latino Soap Opera themselves. Meanwhile, Claudia and Steve investigate a strange accident at a university that leads them to discover an artifact that literally duplicates its users.

The team tries to free Claire from Benedict Valda of the alternate reality, as he controls her using an Artifact and tries to shift the Warehouse to China. Can the team stop that from happening?

The team shares stories of their defining moments. Pete has a hard time accepting the end of Warehouse 13. Claudia has a difficult time accepting her future role as the Warehouse caretaker.